Show Inhibitors 7 entries. The two sites show an unusually high degree of cooperativity with complex interactions between effectors and a fine-tuning of their physiological effects. SCOPe 1h CATH 1h Enterobacteria phage T4;. SCOPe 1h7a. CATH 1h7a. SCOPe 1h7b. CATH 1h7b.
SCOPe 1hk8. CATH 1hk8.
The anaerobic reductase thus has an alpha2beta2 structure. Show Subunits 5 entries. Carbon dioxide is formed from formate, which is present as a cofactor. The formate first forms a formyl radical. The next step, where the formyl radical protonates the 3'-keto group of the substrate, is rate limiting with a calculated total barrier of Zero-point and entropy effects are quite significant in lowering the barrier. C-terminal region contains a Zn Cys 4 center structurally related to the zinc ribbon motif and to rubredoxin and rubrerythrin.
Show Crystallization 2 entries. Show Purification 1 entry. Show Cloned 4 entries. Mutant is able to undergo truncation at the site of the glycyl radical when the radical-containing enzyme is exposed to oxygen. Show Engineering 21 entries. Mice inoculated with the wild-type strain display significantly more severe arthritis, with significantly more synovitis and destruction of the bone and cartilage versus mice inoculated with a NrdDG mutant strain.
The persistence of bacteria in the kidneys is significantly more pronounced in the group inoculated with the wild-type strain. Show Application 2 entries.
OF AA. Enterobacteria phage T4. Show Sequence. Show AA Sequence 6 entries. Logan, D.
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A metal-binding site in the catalytic subunit of anaerobic ribonucleotide reductase. Eliasson, R. The mechanism of the anaerobic Escherichia coli ribonucleotide reductase investigated with nuclear magnetic resonance spectroscopy. Wei, Y. A chemically competent thiosulfuranyl radical on the Escherichia coli class III ribonucleotide reductase.
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Characterization of components of the anaerobic ribonucleotide reductase system from Escherichia coli. Mulliez, E. An iron-sulfur center and a free radical in the active anaerobic ribonucleotide reductase of Escherichia coli.
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Allosteric control of the substrate specificity of the anaerobic ribonucleotide reductase from Escherichia coli. Ollagnier, S. The anaerobic Escherichia coli ribonucleotide reductase. Subunit structure and iron sulfur center. Activation of the anaerobic ribonucleotide reductase from Escherichia coli.
The essential role of the iron-sulfur center for S-adenosylmethionine reduction. Localization and characterization of two nucleotide-binding sites on the anaerobic ribonucleotide reductase from bacteriophage T4. Escherichia virus T4, Escherichia virus T4 P Andersson, J. Allosteric regulation of the class III anaerobic ribonucleotide reductase from bacteriophage T4. Cysteines involved in radical generation and catalysis of class III anaerobic ribonucleotide reductase.
A protein engineering study of bacteriophage T4 NrdD. Torrents, E. The anaerobic ribonucleotide reductase from Lactococcus lactis. Interactions between the two proteins NrdD and NrdG. Iron-sulfur interconversions in the anaerobic ribonucleotide reductase from Escherichia coli. The substrate reaction mechanism of class III anaerobic ribonucleotide reductase.
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Kirdis, E. Ribonucleotide reductase class III, an essential enzyme for the anaerobic growth of Staphylococcus aureus, is a virulence determinant in septic arthritis. The anaerobic ribonucleoside triphosphate reductase from Escherichia coli requires S-adenosylmethionine as a cofactor. Formate is the hydrogen donor for the anaerobic ribonucleotide reductase from Escherichia coli. Show References 17 entries. InterPro database of protein families, domains and functional sites.
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They should perform the stipulations and pillars. They should have humility and humbleness in their hearts: those who are humble in their prayers .
By reciting the surah He should take on the conduct of the angels. In the row of the prayer he should remember the rows of the folk of limpidness. In the bowing he should be reverent, in the prostration reach the place of witnessing, and in the bearing witness He should contemplate the Real.
He should send the ease of blessings to the spirit of the Prophet, and with his own greeting of peace make people safe from his trial. Someone who prays like this is following the Messenger, and a prayer like this demands to be accepted. Its result is the approval of the forgiving Lord. He says that they will be in the fire of Hell on the Day of Judgement and they will abide therein forever.
This means that they will remain in it and they will have no way out of it and they will not cease being in it. Then Allah informs about the situation of the righteous people who believed in their hearts and performed righteous deeds with their bodies. He says that they are the best of creation.