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A total of 51 cases and a procedural guide for the ultrastructural pathology laboratory are included.

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The cases were selected according to one of the following four principles: 1 classic cases that were diagnosed readily by light microscopy to facilitate the electron microscopic diagnosis of less "classic" cases; 2 diagnostic cases, those cases for which ultrastructural analysis was essential for the diagnosis; 3 supportive cases, which are those cases where either the light or the electron microscopic diagnosis is supportive and confirmatory to the other; and 4 new facts cases, which are those that establish new knowledge regarding the pathogenesis of disease using electron microscopy as the investigative modality.

The 51 cases are grouped anatomically in eight major categories. Separate indices for presenting symptoms, differential diagnostic groups, ultrastructural pathology criteria, and final diagnostic categories are provided, as well. This guide will be useful to physicians and students of medicine, structure, and disease.

A Text/Atlas

Designed for daily use at the microscope, this book is a new, practical atlas that will enable pathologists to accurately identify diagnostic cell structures and tumors through the use of electron microscopy. The atlas has been especially designed to demonstrate to the pathologist how electron microscopy can be used as a tool for reporting accurate descriptions and interpretations of tumors.

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This is accomplished using carefully selected micrographs of diagnostically important tumor cell organelles and detailed but concise descriptive text that clearly describes tumor cell organelles to aid the pathologist in identifying them as distinctive cell structures. This text book is a compendium on the subject that presents pathologists and scientists with concise, up-to-date information about the ultrastructure of human tumors. It is based on the examination of over 6, human tumors over many years and a critical review of the literature.

It is the current standard for diagnostic electron microscopy in the field of human tumor pathology.

Published by: Raven Press, Ltd. Anderson Cancer Center, Houston Texas.

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Tel: ext. This exceptional CD-ROM effectively uses a multimedia approach with a combination of detailed animations, nearly high-quality clinical photographs, and over full-color and black-and-white drawings to demonstrate how to microscopically differentiate normal cellular components from neoplastic cellular components in central nervous system biopsies from primary and metastatic CNS neoplasms. This chapter provides an overview of the instances in which EM is most helpful in the specific diagnosis of infectious diseases.

An understanding of the ultrastructural and diagnostic features of certain viruses, bacteria, fungi, and.

1st Edition

EM is the best catchall technique that does not rely on any a priori suspicions of the possible etiologic agent. In addition to a diagnostic role, transmission EM may be valuable for proper therapy and prognosis and in avoiding additional and unnecessary invasive procedures for clinical workup, especially in neonates. The scope of this book is limited to the histological diagnosis of salivary gland tumors. The main goals are to detail diagnostic criteria for the various benign and malignant tumors and to provide appropriate and comprehensive illustrations photographs of which are in full color to assist pathologists in categorizing salivary gland tumors.

Reference Texts Section

This chapter on Ewings Sarcoma family of tumors reviews the epidemiology, molecular features, biology, histopathology, immunocytochemistry, ultrastructure, treatment and prognosis. This tumor family ranges from the classic typical Ewings Sarcoma to the peripheral primitive neuroectodermal tumors. It also discusses a relatively new entity, Biphenotypic Sarcoma, which shares features of Ewings sarcoma and rhabdomyoblastoma while expressing molecular markers characteristic for Ewings sarcoma family of tumors.

Cambridge, England, Cambridge University Press , Reviewed by Juan P.

Palezzo in Modern Pathology, February , vol. Palezzo says in part: "This book presents the current applications of electron microscopy and immunohistochemistry in the diagnosis of this group of tumors.